![]() Positive Control:Positive control gives a response to the experiment. Negative Control:Negative control gives a negative result. Positive Control:Positive control gives positive result Negative Control:A negative control is an experimental control that does not give a response to the test. Positive Control: A positive control is an experimental control that gives a positive result at the end of the experiment. Difference Between Positive and Negative Control Definition For example, the effect of contaminants on an experiment can be indicated. ![]() Hence, negative controls are helpful in identifying outside influences on the experiment. In order to get a good result from the negative control, one should ensure that there is no net response to the test. The negative control is used to confirm that there is no response to the reagent or the microorganism (or any other parameter) used in the test. It is done parallel to the experiment as a control experiment. The negative control is also not exposed to the experimental test directly. If the positive control does not give the expected result, it should be done again and again (by varying different parameters) until a positive result is given.Ī negative control is an experimental control that does not give a response to the test. Once the positive result is given, the test can be used for the experimental treatment. This positive result ensures the success of the test. The positive control is used to get the expected result. The positive control is not exposed to the experimental test it is done parallel to it. Hence, positive controls are used to evaluate the validity of a test. ![]() It is a good indication to know if the test works. This type of test always gives the result as a “yes”. Key Terms: Assay, Control, Experiment, Negative Control, Positive ControlĪ positive control is an experimental control that gives a positive result at the end of the experiment. What is the Difference Between Positive and Negative Control The main difference between positive and negative control is that positive control gives a response to the experiment whereas negative control does not give any response. An experiment can be positively or negatively controlled. (The things that are changing in an experiment are called variables). It can be defined as an experiment that is designed to minimize the effect of variables other than the independent variables. Scientific control is a methodology that tests integrity in experiments by isolating variables as dictated by the scientific method in order to make a conclusion about such variables. Main Difference – Positive vs Negative Control
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